TTC8 anticorps (Internal Region)

N° du produit ABIN498031

Cet anticorps Chèvre Polyclonal détecte spécifiquement TTC8 dans WB et EIA. Il présente une réactivité envers Humain, Souris, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour TTC8 anticorps (Internal Region) (ABIN498031)

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-TTC8 anticorps

Épitope: Internal Region

Séquence: C-KEVLKQDNTH VE

Specificité: This antibody is expected to recognize all reported isoforms (NP_653197.2, NP_938051.1, NP_938052.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine and Porcine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the Internal region of the protein sequence according to NP_653197.2, NP_938051.1, NP_938052.1.

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.2-0.6 μg/mL. Approx 60 kDa band observed in Human Testis lysates(calculated MW of 58.0 kDa according to NP_653197.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TTC8

Antigène: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Autre désignation: TTC8 / BBS8

Sujet: Defects in TTC8 are the cause of Bardet-Biedl syndrome type 8 (BBS8). This is a genetically heterogeneous, autosomal recessive disorder and the primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.Synonyms: Bardet-Biedl syndrome 8 protein, TPR repeat protein 8, Tetratricopeptide repeat protein 8

ID gène: 123016

NCBI Accession: NP_653197

UniProt: Q8TAM2

Pathways: Signalisation Hedgehog